Lupron Depot
LUPRON DEPOT (leuprolide acetate for depot suspension) 3.75 mg for 1-month and 11.25 mg for 3-month administration are used for the management of endometriosis, including pain relief and reduction of endometriotic lesions. LUPRON DEPOT with daily norethindrone acetate 5 mg is also indicated for initial management of endometriosis and for management of recurrence of symptoms. The recommended initial treatment is no more than 6 months. Repeat treatment for endometriosis should be limited to 6 months.
Thinning of the bones may occur during therapy with LUPRON DEPOT, which may not be completely reversible in some patients. Since some conditions may increase the possibility of bone thinning, you should tell your doctor if you smoke, use alcohol in excess, have a family history of osteoporosis (thinning of the bones with fractures), or are taking other medications that can cause thinning of the bones.
After beginning LUPRON DEPOT, your estrogen levels will increase for 1 or 2 weeks. During this time, you may notice an increase in your current symptoms. You should notify your doctor if you develop any new or worsened symptoms after beginning LUPRON DEPOT treatment.
LUPRON DEPOT is not a method of birth control. Even though you may not have periods, unprotected intercourse could result in pregnancy. You should use non-hormonal birth control such as condoms, a diaphragm with contraceptive jelly, or an IUD to prevent pregnancy. If you think you have become pregnant while on LUPRON DEPOT, talk to your doctor immediately.
You should not take norethindrone acetate with LUPRON DEPOT if you currently have or have previously had any clotting disorder, heart disease, stroke, impaired liver function or liver disease, or breast cancer.
Tell your healthcare provider before beginning treatment with norethindrone acetate if you currently have or have previously had high cholesterol, migraines, epilepsy, or depression, or smoke.
During treatment with LUPRON DEPOT and norethindrone acetate as add-back therapy, immediately tell your doctor if you have a sudden loss of vision, double vision, or if migraine headaches occur. You should notify your doctor if you experience fluid retention, seizure, asthma or worsening of asthmatic symptoms, or heart or kidney problems.
There is a possibility of the development or worsening of depression and/or the occurrence of forgetfulness. Patients who have a history of depression should be carefully observed during treatment.
The most common side effects of LUPRON DEPOT include hot flashes, vaginal dryness, headaches, changes in mood, decreased interest in sex, depression, and the occurrence of forgetfulness.
View the complete prescribing information here.
Another great resource is EndoFacts here.
Thinning of the bones may occur during therapy with LUPRON DEPOT, which may not be completely reversible in some patients. Since some conditions may increase the possibility of bone thinning, you should tell your doctor if you smoke, use alcohol in excess, have a family history of osteoporosis (thinning of the bones with fractures), or are taking other medications that can cause thinning of the bones.
After beginning LUPRON DEPOT, your estrogen levels will increase for 1 or 2 weeks. During this time, you may notice an increase in your current symptoms. You should notify your doctor if you develop any new or worsened symptoms after beginning LUPRON DEPOT treatment.
LUPRON DEPOT is not a method of birth control. Even though you may not have periods, unprotected intercourse could result in pregnancy. You should use non-hormonal birth control such as condoms, a diaphragm with contraceptive jelly, or an IUD to prevent pregnancy. If you think you have become pregnant while on LUPRON DEPOT, talk to your doctor immediately.
You should not take norethindrone acetate with LUPRON DEPOT if you currently have or have previously had any clotting disorder, heart disease, stroke, impaired liver function or liver disease, or breast cancer.
Tell your healthcare provider before beginning treatment with norethindrone acetate if you currently have or have previously had high cholesterol, migraines, epilepsy, or depression, or smoke.
During treatment with LUPRON DEPOT and norethindrone acetate as add-back therapy, immediately tell your doctor if you have a sudden loss of vision, double vision, or if migraine headaches occur. You should notify your doctor if you experience fluid retention, seizure, asthma or worsening of asthmatic symptoms, or heart or kidney problems.
There is a possibility of the development or worsening of depression and/or the occurrence of forgetfulness. Patients who have a history of depression should be carefully observed during treatment.
The most common side effects of LUPRON DEPOT include hot flashes, vaginal dryness, headaches, changes in mood, decreased interest in sex, depression, and the occurrence of forgetfulness.
View the complete prescribing information here.
Another great resource is EndoFacts here.
Visanne
VISANNE (dienogest) is used for the management of pelvic pain associated with endometriosis. Dienogest belongs to the class of medications called progestins, medications that act like progesterones in the body. They are produced by the body and are necessary along with other hormones for normal female sexual development and for the regulation of the menstrual cycle. Progestins reduce the effects of estrogen on tissues such as the endometrium (lining of the uterus) and the breast. By reducing the growth effect of estrogen on the endometrium, dienogest helps to reduce the pelvic pain experienced by women with endometriosis.
Mirena
Mirena is a small, T-shaped intrauterine device (IUD) that is placed into the uterus by a trained healthcare provider. Mirena (levonorgestrel-releasing intrauterine system) is a hormone-releasing IUD that prevents pregnancy for up to 5 years. Mirena also treats heavy periods in women who choose intrauterine contraception. Women with Endometriosis use this as treatment mainly to control their periods.
Danazol
This medication is used in women to treat pelvic pain and infertility due to a certain uterus disorder (endometriosis)
Danazol is an androgen similar to testosterone. For the treatment of endometriosis and fibrocystic breast disease, it works by decreasing the amount of hormones made by the ovaries. These hormones usually make the conditions worse. For the treatment of angioedema, danazol helps to increase the amount of a certain protein in your body's defense system (immune system).
Danazol is an androgen similar to testosterone. For the treatment of endometriosis and fibrocystic breast disease, it works by decreasing the amount of hormones made by the ovaries. These hormones usually make the conditions worse. For the treatment of angioedema, danazol helps to increase the amount of a certain protein in your body's defense system (immune system).
Fibristal
Fibristal shown to significantly control heavy uterine bleeding, shrink fibroid volume and reduce pelvic pain for patients suffering from uterine fibroids. Fibristal is a once-daily oral medication that is the first and only non-surgical treatment specifically indicated to treat the signs and symptoms of uterine fibroids. In long term clinical studies Fibristal was shown to safely and effectively control excessive uterine bleeding, shrink fibroid volume and reduce the significant pain and symptom associated with symptomatic uterine fibroids.
Surgery
- Hysterectomy- Surgical removal of the uterus. It may also involve removal of the cervix, ovaries, fallopian tubes and other surrounding structures.
- Oophorectomy- Surgical removal of an ovary or ovaries.
- Laparoscopy- An operation performed in the abdomen or pelvis through small incisions with the aid of a camera. It can either be used to inspect and diagnose a condition or to perform surgery.
- Ablation- A medical procedure that is used to remove or destroy the endometrial lining of the uterus in women who have heavy menstrual bleeding.
- Excision- Laparoscopic resection of endometriosis, refers to the excision (removal) of endometriotic implants. This is a type of conservative management of endometriosis. The goal of conservative surgery is to improve symptoms while preserving the uterus, tubes and ovaries as much as possible.
Medication
- Birth control pills
- Anti-inflammatory (ibuprofen, etc)
- Opioids (T3s, morphine, etc)
- Cannabis (see cannabis section here)
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